| Rank | Season | Player | 100-Yd Rushing Games |
|---|
| 1 | 1998 | Adrian Peterson | 6 |
| 2 | 1999 | Adrian Peterson | 5 |
| 3 | 2007 | Jayson Foster | 4 |
| 4 | 2014 | Matt Breida | 2 |
| 5 | 1998 | Greg Hill | 2 |
| 6 | 2021 | Logan Wright | 1 |
| 7 | 2015 | Matt Breida | 1 |
| 8 | 2012 | Jerick McKinnon | 1 |
| 9 | 2011 | Dominique Swope | 1 |
| 10 | 2007 | Lamar Lewis | 1 |
| 11 | 2006 | Chris Covington | 1 |
| 12 | 2003 | Jermaine Austin | 1 |
| 13 | 2000 | Adrian Peterson | 1 |
| 14 | 1999 | Greg Hill | 1 |
| 15 | 1997 | Greg Hill | 1 |
| 16 | 1996 | Roderick Russell | 1 |
| 17 | 1989 | Joe Ross | 1 |
| 18 | 1982 | Melvin Bell | 1 |